Bioreactor Cell Culture

Critical contamination points for a bioreactor are the transitions between sterile spaces such as the stirrer ports and gas lines.

Bioreactor cell culture.

In one case a bioreactor is a vessel in which a chemical process is carried out which involves organisms or biochemically active substances derived from such organisms. Bioreactor is defined as a vessel that carries out a biological reaction and is used to culture aerobic cells for conducting cellular or enzymatic immobilization. Optimally suited for production of mabs vaccines recombinant proteins and in cell and gene therapy applications the systems support many different types of cell lines and processes including. One bacterial spore or vegetative bacterial cell is all it takes to overgrow an animal cell culture.

Cell cultures are particularly susceptible to biological contamination. Pall s high performance single use stirred tank bioreactors bring superior mixing and mass transfer and support higher cell densities the design and development of single use equipment that fully. This process can either be aerobic or anaerobic these bioreactors are commonly cylindrical ranging in size from litres. Cell culture process simplification from vial to product.

A bioreactor refers to any manufactured device or system that supports a biologically active environment. Sartorius stedim biotech supplies the widest range of cell culture bioreactors for research and development work through to pilot and cgmp manufacture. The icellis bioreactor system is an automated single use fixed bed bioreactor that provides excellent cell growth conditions for adherent cells.